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A.DanC.et al (2013)

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Sources: BPC-157, often referred to as a body protective compound, is recognized for enhancing angiogenesis, the process of forming new blood vessels, which contributes to the strengthening and rebuilding of tissues

doi: 10.1186/s40478-015-0186-2 234

Research shows that in senescent cells, p53 levels are maintained low through ubiquitination while its pro-apoptotic activity is repressed through nuclear segregation by FOXO4. The peptide's competitive inhibition restores p53 activity by promoting nuclear exclusion, allowing p53 to execute its pro-apoptotic program and eliminate senescent cells through targeted pathway activation

The samples were diluted in RIPA, mixed with Laemmli buffer (Bio-Rad, Hercules, CA), and then denatured at 95C for 5 min